Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study.

doi:10.1371/journal.pone.0011690

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Article

Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study.

PloS one - 22 Jul 2010

Bi Mark, Kao Wen Hong Linda, Boerwinkle Eric, Hoogeveen Ron C, Rasmussen-Torvik Laura J, Astor Brad C, North Kari E, Coresh Josef, Köttgen Anna

Abstract excerpt

OBJECTIVE: The minor T-allele of rs780094 in the glucokinase regulator gene (GCKR) associates with a number of metabolic traits including higher triglyceride levels and improved glycemic regulation in study populations of mostly European ancestry. Using data from the Atherosclerosis Risk in Communities (ARIC) Study, we sought to replicate these findings, examine them in a large population-based sample of African...

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PMID: 20661421
DOI: 10.1371/journal.pone.0011690
PMCID: PMC2908550

Genes

GCKR
CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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