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Depletion of Natural Killer Cells improve cholestasis in a murine model of primary biliary cholangitis

2023-06-02

Abstract excerpt

<h4>Background: </h4> and Objective: The aim of this study is to investigate the role of NK cells and their phenotypes in xenobiotic induced murine model of primary biliary cholangitis （PBC）by eliminating NK cells. <h4>Methods:</h4> C57BL/6 female mice were immunized with 2OA-BSA and poly I:C to develop the murine model of PBC. Serologic, histologic, and immunologic testing of PBC mice were analyzed by depleting N...

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Literature Corpus work
688b36b8-8240-5960-b98f-2641b1782b24
DOI
10.21203/rs.3.rs-2978477/v1
Open publication

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