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Article

Anti-CD40 ligand monoclonal antibody delays the progression of murine autoimmune cholangitis.

Clinical and experimental immunology - 1 Dec 2013

Tanaka H, Yang G-X, Iwakoshi N, Knechtle S J, Kawata K, Tsuneyama K, Leung P, Coppel R L, Ansari A A, Joh T, Bowlus C, Gershwin M E

Abstract excerpt

While there have been significant advances in our understanding of the autoimmune responses and the molecular nature of the target autoantigens in primary biliary cirrhosis (PBC), unfortunately these data have yet to be translated into new therapeutic agents. We have taken advantage of a unique murine model of autoimmune cholangitis in which mice expressing a dominant negative form of transforming growth factor β...

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Source

Open in PubMed Open full text

Identifiers

PMID: 23981074
DOI: 10.1111/cei.12193
PMCID: PMC3826303

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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