Article
Interaction between BDNF rs6265 Met allele and low family cohesion is associated with smaller left hippocampal volume in pediatric bipolar disorder.
Journal of affective disorders - 1 Jan 2016
Zeni Cristian Patrick, Mwangi Benson, Cao Bo, Hasan Khader M, Walss-Bass Consuelo, Zunta-Soares Giovana, Soares Jair C
Abstract excerpt
BACKGROUND: Genetic and environmental factors are implicated in the onset and evolution of pediatric bipolar disorder, and may be associated to structural brain abnormalities. The aim of our study was to assess the impact of the interaction between the Brain-Derived Neurotrophic Factor (BDNF) rs6265 polymorphism and family functioning on hippocampal volumes of children and adolescents with bipolar disorder, and...
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