Article
The impact of familial risk and early life adversity on emotion and reward processing networks in youth at-risk for bipolar disorder.
PloS one - 1 Jan 2019
Hanford Lindsay C, Eckstrand Kristen, Manelis Anna, Hafeman Danella M, Merranko John, Ladouceur Cecile D, Graur Simona, McCaffrey Alicia, Monk Kelly, Bonar Lisa K, Hickey Mary Beth, Goldstein Tina R, Goldstein Benjamin I, Axelson David, Bebko Genna, Bertocci Michele A, Gill Mary Kay, Birmaher Boris, Phillips Mary L
Abstract excerpt
A recently developed risk calculator for bipolar disorder (BD) accounts for clinical and parental psychopathology. Yet, it is understood that both familial predisposition and early life adversity contribute to the development of BD. How the interplay between these two factors influence emotion and reward processing networks in youth at risk for BD remains unclear. In this exploratory analysis, offspring of BD...
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