Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Family-based association study of the BDNF, COMT and serotonin transporter genes and DSM-IV bipolar-I disorder in children.

BMC psychiatry - 4 Feb 2009

Mick Eric, Wozniak Janet, Wilens Timothy E, Biederman Joseph, Faraone Stephen V

Abstract excerpt

BACKGROUND: Over the past decade pediatric bipolar disorder has gained recognition as a potentially more severe and heritable form of the disorder. In this report we test for association with genes coding brain-derived neurotrophic factor (BDNF), the serotonin transporter (SLC6A4), and catechol-O-methyltransferase (COMT). METHODS: Bipolar-I affected offspring triads (N = 173) were drawn from 522 individuals with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Bipolar Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain-Derived Neurotrophic Factor

Share to Catechol O-Methyltransferase

Share to Genome-Wide Association Study

Share to Nuclear Family

Share to Serotonin Plasma Membrane Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 19193231
DOI: 10.1186/1471-244X-9-2
PMCID: PMC2640390

Genes

BDNF
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Family-based association study of the BDNF, COMT and serotonin transporter genes and DSM-IV bipolar-I disorder in children.PMID 19193231Read ↗

BDNF Val66Met polymorphism and peripheral protein levels in pediatric bipolar disorder and attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

Linkage disequilibrium of the brain-derived neurotrophic factor Val66Met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype.Semantic proximity Read ↗

Meta-analysis of brain-derived neurotrophic factor p.Val66Met in adult ADHD in four European populations.Semantic proximity Read ↗

Association study of brain-derived neurotrophic factor in adults with a history of childhood onset mood disorder.Semantic proximity Read ↗

Family based association study of pediatric bipolar disorder and the dopamine transporter gene (SLC6A3).Semantic proximity Read ↗

No evidence for preferential transmission of common valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor gene (BDNF) in ADHD.Semantic proximity Read ↗

Case-control and within-family tests for association between 5HTTLPR and conduct problems in a longitudinal adolescent sample.Semantic proximity Read ↗

Serotonin transporter gene (HTTLPR) is not in linkage disequilibrium with prepubertal and early adolescent bipolarity.Semantic proximity Read ↗

Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression.Semantic proximity Read ↗

GAD1 single nucleotide polymorphism is in linkage disequilibrium with a child bipolar I disorder phenotype.Semantic proximity Read ↗

Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD.Semantic proximity Read ↗

Family-based association test of the 5HTTLPR and aggressive behavior in a general population sample of children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.