Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A GWAS SNP for Schizophrenia Is Linked to the Internal MIR137 Promoter and Supports Differential Allele-Specific Expression.

Schizophrenia bulletin - 1 Jul 2016

Warburton Alix, Breen Gerome, Bubb Vivien J, Quinn John P

Abstract excerpt

Single nucleotide polymorphisms (SNPs) within the MIR137 gene locus have been shown to confer risk for schizophrenia through genome-wide association studies (GWAS). The expression levels of microRNA-137 (miR-137) and its validated gene targets have also been shown to be disrupted in several neuropsychiatric conditions, including schizophrenia. Regulation of miR-137 expression is thus imperative for normal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Culture Techniques
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Genome-Wide Association Study

Share to MicroRNAs

Share to Minisatellite Repeats

Share to Promoter Regions, Genetic

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 26429811
DOI: 10.1093/schbul/sbv144
PMCID: PMC4903043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A GWAS SNP for Schizophrenia Is Linked to the Internal MIR137 Promoter and Supports Differential Allele-Specific Expression.PMID 26429811Read ↗

Identification and Potential Regulatory Properties of Evolutionary Conserved Regions (ECRs) at the Schizophrenia-Associated MIR137 Locus.Semantic proximity Read ↗

The SNP rs1625579 in miR-137 gene and risk of schizophrenia in Chinese population: A meta-analysis.Semantic proximity Read ↗

A comprehensive review of the genetic and biological evidence supports a role for MicroRNA-137 in the etiology of schizophrenia.Semantic proximity Read ↗

Polymorphisms in MIR137HG and microRNA-137-regulated genes influence gray matter structure in schizophrenia.Semantic proximity Read ↗

Impact of a microRNA MIR137 susceptibility variant on brain function in people at high genetic risk of schizophrenia or bipolar disorder.Semantic proximity Read ↗

Genome-wide association study identifies five new schizophrenia loci.Semantic proximity Read ↗

Replication of GWAS identified miR-137 and its target gene polymorphisms in Schizophrenia of South Indian population and meta-analysis with Psychiatric Genomics Consortium.Semantic proximity Read ↗

A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder.Semantic proximity Read ↗

The genome-wide supported microRNA-137 variant predicts phenotypic heterogeneity within schizophrenia.Semantic proximity Read ↗

MIR137 gene and target gene CACNA1C of miR-137 contribute to schizophrenia susceptibility in Han Chinese.Semantic proximity Read ↗

Schizophrenia risk-associated SNPs affect expression of microRNA 137 host gene: a postmortem study.Semantic proximity Read ↗

No evidence of an association between MIR137 rs1625579 and schizophrenia in Asians: a meta-analysis in 30 843 individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.