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Article

TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen.

BMC medical genomics - 1 Oct 2015

Marquard Andrea Marion, Birkbak Nicolai Juul, Thomas Cecilia Engel, Favero Francesco, Krzystanek Marcin, Lefebvre Celine, Ferté Charles, Jamal-Hanjani Mariam, Wilson Gareth A, Shafi Seema, Swanton Charles, André Fabrice, Szallasi Zoltan, Eklund Aron Charles

Abstract excerpt

BACKGROUND: A substantial proportion of cancer cases present with a metastatic tumor and require further testing to determine the primary site; many of these are never fully diagnosed and remain cancer of unknown primary origin (CUP). It has been previously demonstrated that the somatic point mutations detected in a tumor can be used to identify its site of origin with limited accuracy. We hypothesized that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26429708
DOI: 10.1186/s12920-015-0130-0
PMCID: PMC4590711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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