Article
Functional relevance for type 1 diabetes mellitus-associated genetic variants by using integrative analyses.
Human immunology - 1 Oct 2015
Qiu Ying-Hua, Deng Fei-Yan, Tang Zai-Xiang, Jiang Zhen-Huan, Lei Shu-Feng
Abstract excerpt
AIM: Type 1 diabetes mellitus (type 1 DM) is an autoimmune disease. Although genome-wide association studies (GWAS) and meta-analyses have successfully identified numerous type 1 DM-associated susceptibility loci, the underlying mechanisms for these susceptibility loci are currently largely unclear. METHODS: Based on publicly available datasets, we performed integrative analyses (i.e., integrated gene...
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