Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional mechanisms for type 2 diabetes-associated genetic variants.

Journal of diabetes and its complications - 1 Jan 2000

Zhu Xiao-Wei, Deng Fei-Yan, Wu Long-Fei, Tang Zai-Xiang, Lei Shu-Feng

Abstract excerpt

AIMS: Type 2 diabetes (T2D) is a complex endocrine and metabolic disorder, characterized by hyperglycemia due to insulin resistance and relative lack of insulin. Several recent studies have identified a large number of genetic loci associated with T2D without exploring functional mechanisms underlying the associations. This study established integrative analyses to detect the functional mechanisms for T2D-related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Genetic Association Studies

Share to Neuregulin-1

Share to Proteins

Share to Quantitative Trait Loci

Share to RNA-Binding Proteins

Source

Identifiers

PMID: 25754502
DOI: 10.1016/j.jdiacomp.2015.02.007

Genes

NRG1
RBMS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional mechanisms for type 2 diabetes-associated genetic variants.PMID 25754502Read ↗

In silico functional and pathway analysis of risk genes and SNPs for type 2 diabetes in Asian population.Semantic proximity Read ↗

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.Semantic proximity Read ↗

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Semantic proximity Read ↗

Multi-Omics Analysis Revealed the rSNPs Potentially Involved in T2DM Pathogenic Mechanism and Metformin Response.Semantic proximity Read ↗

Functional relevance for type 1 diabetes mellitus-associated genetic variants by using integrative analyses.Semantic proximity Read ↗

Data interpretation: deciphering the biological function of Type 2 diabetes associated risk loci.Semantic proximity Read ↗

Mechanisms of Type 2 Diabetes Risk Loci.Semantic proximity Read ↗

High-Resolution Genetic Maps Identify Multiple Type 2 Diabetes Loci at Regulatory Hotspots in African Americans and Europeans.Semantic proximity Read ↗

Functional annotation of sixty-five type-2 diabetes risk SNPs and its application in risk prediction.Semantic proximity Read ↗

Integrating Genome-Wide Association and eQTLs Studies Identifies the Genes and Gene Sets Associated with Diabetes.Semantic proximity Read ↗

Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity.Semantic proximity Read ↗

Functional Variants Identified Efficiently through an Integrated Transcriptome and Epigenome Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.