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Article

LRP1B deletion is associated with poor outcome for glioblastoma patients.

Journal of the neurological sciences - 15 Nov 2015

Tabouret E, Labussière M, Alentorn A, Schmitt Y, Marie Y, Sanson M

Abstract excerpt

INTRODUCTION: Deletion of the tumor suppressor gene LRP1B has been reported in glioblastoma, the most aggressive primary brain tumor in adults. Our objective was to analyze frequency and prognostic impact of LRP1B deletion and expression levels. METHODS: We retrospectively included all the primary IDH1/2 wild-type GBM patients with available clinical follow-up, DNA and RNA from our database. Deletions were...

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Source

Identifiers

PMID: 26428308
DOI: 10.1016/j.jns.2015.09.345

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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