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Article

LRP1B in cancer: From a mutation landscape to predictive biomarkers for precision oncology.

Mutation research. Reviews in mutation research - 1 Jan 2025

Yang Likun, Wang Ximo, Yu Xiangyang, Xun Jing

Abstract excerpt

Low-density lipoprotein receptor-related protein 1B (LRP1B) is one of the most frequently mutated genes across a wide range of malignancies and has garnered increasing attention owing to its crucial role in tumorigenesis and clinical outcomes. Emerging evidence suggests that LRP1B mutations not only disrupt essential cellular processes such as proliferation, migration, and genomic stability but also significantly...

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Identifiers

PMID: 41218518
DOI: 10.1016/j.mrrev.2025.108568

Genes

LRP1B

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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