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Article

The Prevalence and Prognostic Implications of BRAF K601E Mutations in Thyroid Neoplasms: A Systematic Review and Meta-Analysis.

Head & neck - 1 Dec 2024

Webster Alyssa, Elshazli Rami M, Pinion Dylan, Clark Robert D E, Kelly Grace, Issa Peter P, Hussein Mohammad H, Fawzy Manal S, Toraih Eman A, Kandil Emad

Abstract excerpt

BACKGROUND: Activating mutations in the BRAF oncogene occur in 45% of papillary thyroid carcinomas (PTCs). Though less studied, K601E may identify a clinically distinct subset of thyroid neoplasms. METHODS: A bioinformatics assessment was conducted using the COSMIC database and in silico data analysis. A systematic search was conducted through August 2024 to identify studies reporting BRAF mutation in thyroid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39400963
DOI: 10.1002/hed.27950

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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