Article
Preoperative Role of RAS or BRAF K601E in the Guidance of Surgery for Indeterminate Thyroid Nodules.
World journal of surgery - 1 Jul 2020
Ravella L, Lopez J, Descotes F, Giai J, Lapras V, Denier M-L, Borson-Chazot F, Lifante J-C, Decaussin-Petrucci M
Abstract excerpt
BACKGROUND: RAS and K601E BRAF mutations are not a reliable indicator of malignancy in fine-needle aspirations (FNA) of thyroid indeterminate cytologic nodules. We aimed to evaluate the histologic characteristics, the risk of malignancy associated with such mutations in FNA and their potential interest for preoperative clinical management of nodules. METHODS: We evaluated 69 indeterminate thyroid nodules with RAS...
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