Article
Linkage and whole genome sequencing identify a locus on 6q25-26 for formal thought disorder and implicate MEF2A regulation.
Schizophrenia research - 1 Dec 2015
Thygesen Johan Hilge, Zambach Sine Katharina, Ingason Andrés, Lundin Pär, Hansen Thomas, Bertalan Marcelo, Rosengren Anders, Bjerre Ditte, Ferrero-Miliani Laura, Rasmussen Henrik Berg, Parnas Josef, Werge Thomas
Abstract excerpt
Formal thought disorder is a major feature of schizophrenia and other psychotic disorders. It is heritable, found in healthy relatives of patients with schizophrenia and other mental disorders but knowledge of specific genetic factors is lacking. The aim of this study was to search for biologically relevant high-risk variants. Formal thought disorder was assessed in participants in the Copenhagen Schizophrenia...
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