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Article

Comprehensive gene-based association study of a chromosome 20 linked region implicates novel risk loci for depressive symptoms in psychotic illness.

PloS one - 1 Jan 2011

Bigdeli T Bernard, Maher Brion S, Zhao Zhongming, Oord Edwin J C G van den, Thiselton Dawn L, Sun Jingchun, Webb Bradley T, Amdur Richard L, Wormley Brandon, O'Neill Francis A, Walsh Dermot, Riley Brien P, Kendler Kenneth S, Fanous Ayman H

Abstract excerpt

BACKGROUND: Prior genomewide scans of schizophrenia support evidence of linkage to regions of chromosome 20. However, association analyses have yet to provide support for any etiologically relevant variants. METHODS: We analyzed 2988 LD-tagging single nucleotide polymorphisms (SNPs) in 327 genes on chromosome 20, to test for association with schizophrenia in 270 Irish high-density families (ISHDSF, N = 270...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22220189
DOI: 10.1371/journal.pone.0021440
PMCID: PMC3248394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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