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Article

A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia.

American journal of human genetics - 1 Apr 2007

Choudhury Khalid, McQuillin Andrew, Puri Vinay, Pimm Jonathan, Datta Susmita, Thirumalai Srinivasa, Krasucki Robert, Lawrence Jacob, Bass Nicholas J, Quested Digby, Crombie Caroline, Fraser Gillian, Walker Nicholas, Nadeem Haitham, Johnson Sophie, Curtis David, St Clair David, Gurling Hugh M D

Abstract excerpt

Previous linkage analyses of families with multiple cases of schizophrenia by us and others have confirmed the involvement of the chromosome 11q22-24 region in the etiology of schizophrenia, with LOD scores of 3.4 and 3.1. We now report fine mapping of a susceptibility gene in the 11q22-24 region...

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Identifiers

PMID: 17357072
DOI: 10.1086/513475
PMCID: PMC1852702

Genes

FXYD6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17357072-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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