Article
A genetic association study of the FXYD domain containing ion transport regulator 6 (FXYD6) gene, encoding phosphohippolin, in susceptibility to schizophrenia in a Japanese population.
Neuroscience letters - 13 Jun 2008
Ito Yoshihito, Nakamura Yukako, Takahashi Nagahide, Saito Shinichi, Aleksic Branko, Iwata Nakao, Inada Toshiya, Ozaki Norio
Abstract excerpt
The FXYD domain containing ion transport regulator 6 (FXYD6) gene is located within a region of chromosome 11 (11q23.3) that has been shown by a number of genome scans to be one of the most well-established linkages to schizophrenia. FXYD6 encodes the protein phosphohippolin, which is primarily expressed in the brain. Phosphohippolin modulates the kinetic activity of Na,K-ATPase and has long-term physiological...
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