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Article

Research of methods to detect genomic mutations induced by CRISPR/Cas systems.

Journal of biotechnology - 20 Nov 2015

Wang Kun, Mei Dong Yi, Liu Qian Nan, Qiao Xiao Huan, Ruan Wei Min, Huang Tian, Cao Geng Sheng

Abstract excerpt

The indel-forming non-homologous end joining (NHEJ) pathway repairs double strand breaks in mammalian genomes, resulting in mutation formation following genome editing. Common techniques employed to identify these mutations include the amplified fragment length polymorphism (AFLP) and SURVEYOR assays, which are time consuming, laborious, and only offer a low level of sensitivity. An alternative to these...

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PMID: 26419205
DOI: 10.1016/j.jbiotec.2015.09.029

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EMX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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