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Article

Improved Survival and Neurological Outcomes after Cardiopulmonary Resuscitation in Toll-like Receptor 4-mutant Mice.

Chinese medical journal - 5 Oct 2015

Xu Li, Zhang Qing, Zhang Qing-Song, Li Qian, Han Ji-Yuan, Sun Peng

Abstract excerpt

BACKGROUND: Toll-like receptor 4 (TLR4) is a crucial receptor in the innate immune system and noninfectious immune responses. It has been reported that TLR4 participates in the pathological course of ischemia/reperfusion (I/R) injury. However, the role of TLR4 in the process of I/R injury after cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) is still unknown. In this study, we investigated the effects...

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Source

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Identifiers

PMID: 26415804
DOI: 10.4103/0366-6999.166024
PMCID: PMC4736870

Genes

TLR4
MPO
TNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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