Back to search

Article

Low-intensity transcranial ultrasound (LITUS) exerts neuroprotective effects by modulating inflammatory responses via the Piezo1-Dkk3/Ca 2+ /PI3K-Akt signaling pathway

2024-02-16

Abstract excerpt

<h4>Background: </h4> Post-cardiac arrest brain injury (PCABI) contributes to unfavorable outcomes following cardiopulmonary resuscitation (CPR) significantly, with effective therapeutic interventions for PCABI remain elusive. Low-intensity transcranial ultrasound (LITUS) has exhibited neuroprotective effects in various disease models, yet the precise mechanisms underlying these effects have not been fully elucida...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
401242c1-18fb-5fe3-b957-b5948687d8f6
DOI
10.21203/rs.3.rs-3932902/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Low-intensity transcranial ultrasound (LITUS) exerts neuroprotective effects by modulating inflammatory responses via the Piezo1-Dkk3/Ca 2+ /PI3K-Akt signaling pathwayDOI 10.21203/rs.3.rs-3932902/v1
Piezo2 contributes to traumatic brain injury by activating the RhoA/ROCK1 pathwaysSemantic proximity
Improvement in Outcomes and Prevention of Multiple Organ Dysfunction Syndrome After Cardiac Arrest and Successful Cardiopulmonary Resuscitation by Systemic Administration of Bumetanide in Male MiceSemantic proximity
Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation in MicrogliaSemantic proximity
A proteomics-based approach reveals the role of the activation of astrocytes with the A1 phenotype in medullary neuroinflammation after TBI in mice.Semantic proximity
The Impact of Environmental Enrichment on Neurological Damage: Mechanistic Study of Ferroptosis Inhibition via Tlr4Semantic proximity
Associations between early CT head findings and clinical characteristics following out-of-hospital cardiac arrestSemantic proximity
MicroRNAs: The New Challenge for Traumatic Brain Injury DiagnosisSemantic proximity
Inhibition of neutrophil extracellular trap formation ameliorates neuroinflammation and neuronal apoptosis via STING-dependent IRE1α/ASK1/JNK signaling pathway in mice with traumatic brain injurySemantic proximity
Protective effect of high n-3/n-6 PUFA ratio on acute hypoxic-ischemic brain damage in mfat-1 transgenic mice and possible inflammation-related targets identified by transcriptome analysisSemantic proximity
Exploring the pathogenesis of traumatic brain injury and traumatic epilepsy based on bioinformatics analysisSemantic proximity
Neuronal nuclear calcium signaling suppression of microglial reactivity is mediated by osteoprotegerin after traumatic brain injurySemantic proximity
Direct neuronal protection by the protease-activated receptor PAR4 antagonist ML354 after experimental stroke in miceSemantic proximity
Select a neighboring publication to make it the new centre.