Article
Evaluation of the iBeads assay as a tool for identifying class I HLA antibodies.
Human immunology - 1 Sept 2015
Visentin Jonathan, Guidicelli Gwendaline, Nong Thoa, Moreau Jean-François, Merville Pierre, Couzi Lionel, Lee Jar-How, Taupin Jean-Luc
Abstract excerpt
In addition to antibodies targeting native class I human leukocyte antigens (HLA), the single antigen flow beads assay (SAFB) detects antibodies recognizing denatured forms (anti-dHLA). Acid treated SAFB and the modified SAFB reagent named iBeads are expected to distinguish anti-native (anti-nHLA) from anti-dHLA. Sera from 280 class I HLA-sensitized SAFB-positive kidney transplant candidates were retested with...
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