Article
Impact of allele-specific anti-human leukocyte antigen class I antibodies on organ allocation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Sept 2023
Yeung Melissa Y, Murakami Naoka, Kafetzi Maria L, Simmons Daimon P, Wood Isabelle, Macaskill Peter, Towle Matthew, DellaGatta Jamie, Stevens Jonathan, Comeau Edward, Baronas Jane, Mohsin Nabil, Chen Mike, Lee Jar-How, Lane William J, Milford Edgar L, Guleria Indira
Abstract excerpt
Technological advances in the field of histocompatibility have allowed us to define anti-human leukocyte antigen (HLA) antibody specificity at the allelic level. However, how allele-specific antibodies affect organ allocation is poorly studied. We examined allelic specificities of class I HLA antibodies in 6726 consecutive serum samples from 2953 transplant candidates and evaluated their impact on the...
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