Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Denatured class I human leukocyte antigen antibodies in sensitized kidney recipients: prevalence, relevance, and impact on organ allocation.

Transplantation - 15 Oct 2014

Visentin Jonathan, Guidicelli Gwendaline, Bachelet Thomas, Jacquelinet Christian, Audry Benoît, Nong Thoa, Dubois Valérie, Moreau Jean-François, Lee Jar-How, Couzi Lionel, Merville Pierre, Taupin Jean-Luc

Abstract excerpt

BACKGROUND: Single antigen flow beads assays may overestimate sensitization because of the detection of supposedly irrelevant antibodies recognizing denatured class I human leukocyte antigens (HLAs). METHODS: Sera of 323 HLA-sensitized kidney transplant candidates positive with a class I HLA single antigen flow beads assay were retested after acid treatment of the beads. Denatured HLA antibodies were identified...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Kidney Injury
Share to Antibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens

Share to Fluorescence

Share to Histocompatibility Antigens Class I

Share to Histocompatibility Testing

Share to Isoantibodies

Share to Kidney Transplantation

Source

Identifiers

PMID: 25289917
DOI: 10.1097/TP.0000000000000229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Denatured class I human leukocyte antigen antibodies in sensitized kidney recipients: prevalence, relevance, and impact on organ allocation.PMID 25289917Read ↗

Impact of allele-specific anti-human leukocyte antigen class I antibodies on organ allocation.Semantic proximity Read ↗

Evaluation of the iBeads assay as a tool for identifying class I HLA antibodies.Semantic proximity Read ↗

Highly sensitised patients awaiting deceased donor renal transplants are disadvantaged by the presence of denatured HLA antibody detected in routine HLA antibody testing.Semantic proximity Read ↗

HLA diversity in ethnic populations can affect detection of donor-specific antibodies by single antigen beadsSemantic proximity Read ↗

Determination of unacceptable HLA antigen mismatches in kidney transplant recipients.Semantic proximity Read ↗

Detection of antibodies to denatured human leucocyte antigen molecules by single antigen Luminex.Semantic proximity Read ↗

Bead‐by‐bead normalization of single antigen assays: A necessary step for accurate detection of weak anti‐HLA antibodiesSemantic proximity Read ↗

Cumulative mean fluorescent intensities of HLA specific antibodies predict antibody mediated rejections after kidney transplantation.Semantic proximity Read ↗

Incidence and impact of allele-specific anti-HLA antibodies and high-resolution HLA genotyping on assessing immunologic compatibility.Semantic proximity Read ↗

Antibodies against HLA-DP recognize broadly expressed epitopes.Semantic proximity Read ↗

Unexpected anti-HLA-DR and -DQ alloantibodies after nephrectomy of an HLA-DR and -DQ identical first renal transplant.Semantic proximity Read ↗

HLA antibody affinity determination: From HLA-specific monoclonal antibodies to donor HLA specific antibodies (DSA) in patient serum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.