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Detection of antibodies to denatured human leucocyte antigen molecules by single antigen Luminex.

HLA - 1 Jan 2021

Gutiérrez-Larrañaga María, Riesco Laura, Guiral Sandra, Irure Juan, Rodrigo Emilio, Ocejo-Vinyals Javier, Martorell Jaume, Caro Jose L, López-Hoyos Marcos, San Segundo David

Abstract excerpt

The anti-HLA antibody detection has been improved in sensitivity and specificity with solid-phase antigen bead (SAB) assays based on Luminex. However, false positive results due to denatured HLA (dHLA) may arise after single antigen test. The aim of this study was to compare the performance of the two Luminex technology-based anti-HLA detection kits available in the market in showing undesired anti-HLA antibody...

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PMID: 33040479
DOI: 10.1111/tan.14098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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