Article
Microfluidic cytometric analysis of cancer cell transportability and invasiveness.
Scientific reports - 25 Sept 2015
Liu Zongbin, Lee Yeonju, Jang Joon hee, Li Ying, Han Xin, Yokoi Kenji, Ferrari Mauro, Zhou Ledu, Qin Lidong
Abstract excerpt
The extensive phenotypic and functional heterogeneity of cancer cells plays an important role in tumor progression and therapeutic resistance. Characterizing this heterogeneity and identifying invasive phenotype may provide possibility to improve chemotherapy treatment. By mimicking cancer cell perfusion through circulatory system in metastasis, we develop a unique microfluidic cytometry (MC) platform to separate...
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