Article
Microfluidic techniques for isolation, formation, and characterization of circulating tumor cells and clusters
15 Jul 2022
Abstract excerpt
Circulating tumor cell (CTC) clusters that are shed from the primary tumor into the bloodstream are associated with a poor prognosis, elevated metastatic potential, higher proliferation rate, and distinct molecular features compared to single CTCs. Studying CTC clusters may give us information on the differences in the genetic profiles, somatic mutations, and epigenetic changes in circulating cells compared to...
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