Article
A microfluidic device for differential capture of heterogeneous rare tumor cells with epithelial and mesenchymal phenotypes.
Analytica chimica acta - 8 Sept 2020
Wang Xiang, Deng Linhong, Gjertsen Bjørn Tore
Abstract excerpt
Accumulating evidence suggests that the features associated with epithelial to mesenchymal transition (EMT) in circulating tumor cells (CTCs) reflect intrinsic metastatic potential and associate with therapy resistance. Thus, profiling the EMT phenotypes of CTCs is increasingly important for cancer diagnosis and prediction of therapeutic responses. However, rapid assessment of the EMT status of a global CTC...
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