Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An integrated microfluidic chip for the capture, migration and molecular phenotyping of single circulating tumor cells.

Biosensors & bioelectronics - 1 Nov 2026

Liang Menghu, Liu Mengfei, Yue Shuai, Feng Yonghui, Zhang Yingzhi, Fang Jin, Xu Zhangrun

Abstract excerpt

Single-cell analysis of circulating tumor cells (CTCs) holds significant potential for elucidating tumor metastasis mechanisms, improving prognosis assessment, and advancing precision therapeutics. Microfluidic chips have emerged as essential tools for isolating and enriching CTCs. However, existing microfluidic techniques have limited capability to achieve in situ functional characterization of single CTCs....

Topics

Join the communities discussing this publication.

Biosensing Techniques
Cell Separation
Epithelial-Mesenchymal Transition
Equipment Design
Lab-On-A-Chip Devices

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microfluidic Analytical Techniques

Neoplastic Cells, Circulating

Single-Cell Analysis

Source

Identifiers

PMID: 42250352
DOI: 10.1016/j.bios.2026.118891

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An integrated microfluidic chip for the capture, migration and molecular phenotyping of single circulating tumor cells.PMID 42250352Read ↗

A Microfluidic Chip for Efficient Circulating Tumor Cells Enrichment, Screening, and Single‐Cell RNA SequencingSemantic proximity Read ↗

A microfluidic device for differential capture of heterogeneous rare tumor cells with epithelial and mesenchymal phenotypes.Semantic proximity Read ↗

Microfluidic techniques for isolation, formation, and characterization of circulating tumor cells and clustersSemantic proximity Read ↗

CTC-Race: Single-Cell Motility Assay of Circulating Tumor Cells from Metastatic Lung Cancer PatientsSemantic proximity Read ↗

Development and clinical validation of a microfluidic-based platform for CTC enrichment and downstream molecular analysisSemantic proximity Read ↗

An Integrated Microfluidic Chip and Its Clinical Application for Circulating Tumor Cell Isolation and Single‐Cell AnalysisSemantic proximity Read ↗

Clinical validation of an ultra high-throughput spiral microfluidics for the detection and enrichment of viable circulating tumor cells.Semantic proximity Read ↗

Advances in microfluidic platforms for tumor cell phenotyping: from bench to bedside.Semantic proximity Read ↗

Establishment of a cascaded microfluidic single cell analysis system for molecular and functional heterogeneity analysis of circulating tumor cellsSemantic proximity Read ↗

Fast and efficient microfluidic cell filter for isolation of circulating tumor cells from unprocessed whole blood of colorectal cancer patientsSemantic proximity Read ↗

High throughput, label-free isolation of circulating tumor cell clusters in meshed microwellsSemantic proximity Read ↗

Advances and critical concerns with the microfluidic enrichments of circulating tumor cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.