Article
A genome-wide association study for colorectal cancer identifies a risk locus in 14q23.1.
Human genetics - 1 Nov 2015
Lemire Mathieu, Qu Conghui, Loo Lenora W M, Zaidi Syed H E, Wang Hansong, Berndt Sonja I, Bézieau Stéphane, Brenner Hermann, Campbell Peter T, Chan Andrew T, Chang-Claude Jenny, Du Mengmeng, Edlund Christopher K, Gallinger Steven, Haile Robert W, Harrison Tabitha A, Hoffmeister Michael, Hopper John L, Hou Lifang, Hsu Li, Jacobs Eric J, Jenkins Mark A, Jeon Jihyoun, Küry Sébastien, Li Li, Lindor Noralane M, Newcomb Polly A, Potter John D, Rennert Gad, Rudolph Anja, Schoen Robert E, Schumacher Fredrick R, Seminara Daniela, Severi Gianluca, Slattery Martha L, White Emily, Woods Michael O, Cotterchio Michelle, Marchand Loic Le, Casey Graham, Gruber Steven B, Peters Ulrike, Hudson Thomas J
Abstract excerpt
Over 50 loci associated with colorectal cancer (CRC) have been uncovered by genome-wide association studies (GWAS). Identifying additional loci has the potential to help elucidate aspects of the underlying biological processes leading to better understanding of the pathogenesis of the disease. We re-evaluated a GWAS by excluding controls that have family history of CRC or personal history of colorectal polyps, as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.