Article
Polymorphisms in the vitamin D receptor and risk of gout in Chinese Han male population.
Rheumatology international - 1 Jun 2015
Liu Shi-guo, Li Yuan-yuan, Sun Rui-xia, Wang Jing-li, Li Xin-de, Han Lin, Chu Nan, Li Chang-gui
Abstract excerpt
Previous studies have showed that patients with gout showed lower serum 25(OH)D levels. As the specific receptor of vitamin D, VDR plays an important role in regulating immune system by combining with vitamin D. In this study, we investigated whether the functional VDR polymorphisms were associated with susceptibility to gout in Chinese Han male population. A total of 504 patients with gout and 523 gout-free...
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