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Pregnancy, Primary Aldosteronism, and Adrenal<i>CTNNB1</i>Mutations

23 Sept 2015

Abstract excerpt

Recent discoveries of somatic mutations permit the recognition of subtypes of aldosterone-producing adenomas with distinct clinical presentations and pathological features. Here we describe three women with hyperaldosteronism, two who presented in pregnancy and one who presented after menopause. Their aldosterone-producing adenomas harbored activating mutations of CTNNB1, encoding β-catenin in the Wnt...

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PMID: 26397949
DOI: 10.1056/nejmoa1504869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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