Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Repression by RB1 characterizes genes involved in the penultimate stage of erythroid development.

Cell cycle (Georgetown, Tex.) - 1 Jan 2015

Zhang Ji, Loyd Melanie R, Randall Mindy S, Morris John J, Shah Jayesh G, Ney Paul A

Abstract excerpt

Retinoblastoma-1 (RB1), and the RB1-related proteins p107 and p130, are key regulators of the cell cycle. Although RB1 is required for normal erythroid development in vitro, it is largely dispensable for erythropoiesis in vivo. The modest phenotype caused by RB1 deficiency in mice raises questions about redundancy within the RB1 family, and the role of RB1 in erythroid differentiation. Here we show that RB1 is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Lineage
Share to E2F Transcription Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Erythroid Cells

Share to Erythropoiesis

Share to Gestational Age

Share to Receptors, Erythropoietin

Share to Retinoblastoma-Like Protein p130

Share to Retinoblastoma Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 26397180
DOI: 10.1080/15384101.2015.1090067
PMCID: PMC4825629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Repression by RB1 characterizes genes involved in the penultimate stage of erythroid development.PMID 26397180Read ↗

RB, the conductor that orchestrates life, death and differentiation.Semantic proximity Read ↗

RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins.Semantic proximity Read ↗

Regulation of GATA1 levels in erythropoiesisSemantic proximity Read ↗

BMI1 regulates human erythroid self-renewal through both gene repression and gene activationSemantic proximity Read ↗

Deregulated E2f-2 underlies cell cycle and maturation defects in retinoblastoma null erythroblasts.Semantic proximity Read ↗

Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage ConversionSemantic proximity Read ↗

Evolving intricacies and implications of E2F1 regulationSemantic proximity Read ↗

The retinoblastoma gene: role in cell cycle control and cell differentiationSemantic proximity Read ↗

An E2F binding-deficient Rb1 protein partially rescues developmental defects associated with Rb1 nullizygosity.Semantic proximity Read ↗

LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis.Semantic proximity Read ↗

E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.Semantic proximity Read ↗

Conserved RB functions in development and tumor suppressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.