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Article

RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins.

Molecular and cellular biology - 1 Oct 1999

Lai A, Lee J M, Yang W M, DeCaprio J A, Kaelin W G, Seto E, Branton P E

Abstract excerpt

Retinoblastoma (RB) tumor suppressor family proteins block cell proliferation in part by repressing certain E2F-specific promoters. Both histone deacetylase (HDAC)-dependent and -independent repression activities are associated with the RB "pocket." The mechanism by which these two repression functions occupy the pocket is unknown. A known RB-binding protein, RBP1, was previously found by our group to be an...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10490602
DOI: 10.1128/MCB.19.10.6632
PMCID: PMC84642

Genes

RBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins.PMID 10490602Read ↗

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