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Article

Light pigmentation phenotype is correlated with increased substantia nigra echogenicity.

Movement disorders : official journal of the Movement Disorder Society - 1 Nov 2015

Rumpf Jost-Julian, Schirmer Maria, Fricke Christopher, Weise David, Wagner Justinus Aspasios, Simon Jan, Classen Joseph

Abstract excerpt

OBJECTIVE: This study was undertaken to address the question of whether pigmentation may be mechanistically linked with Parkinson's disease. METHODS: In a cross-sectional, observational study, 116 healthy subjects received transcranial sonography of the substantia nigra. Pigmentation phenotype was assessed using the Fitzpatrick skin phototype classification, and five additional phenotypic pigmentation traits as...

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Identifiers

PMID: 26395561
DOI: 10.1002/mds.26427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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