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Article

Disturbance of iron metabolism in Parkinson's disease -- ultrasonography as a biomarker.

Neurotoxicity research - 1 Jan 2006

Berg Daniela, Hochstrasser Helmine, Schweitzer Katherine J, Riess Olaf

Abstract excerpt

A central role of iron in the pathogenesis of Parkinson's disease (PD) has been discussed for many years. So far, however, a biomarker indicating increased iron levels in the substantia nigra (SN) in PD patients has been missing. Performing transcranial ultrasound we detected an increased area of SN echogenicity as a typical echofeature in PD, visible already in the early stages of the disease and in subjects...

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Source

Identifiers

PMID: 16464747
DOI: 10.1007/BF03033302

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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