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Article

Dynamics of defective hepatitis C virus clones in reinfected liver grafts in liver transplant recipients: ultradeep sequencing analysis.

Journal of clinical microbiology - 1 Nov 2013

Ohtsuru Shigeru, Ueda Yoshihide, Marusawa Hiroyuki, Inuzuka Tadashi, Nishijima Norihiro, Nasu Akihiro, Shimizu Kazuharu, Koike Kaoru, Uemoto Shinji, Chiba Tsutomu

Abstract excerpt

Hepatitis C virus (HCV) reinfects liver allografts in transplant recipients by replicating immediately after transplantation, causing a rapid increase in blood serum HCV RNA levels. We evaluated dynamic changes in the viral genetic complexity after HCV reinfection of the graft liver; we also identified the characteristics of replicating HCV clones using a massively parallel ultradeep sequencing technique to...

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Identifiers

PMID: 23985907
DOI: 10.1128/JCM.00676-13
PMCID: PMC3889746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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