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High‐throughput diagnostic profiling of clinically actionable gene fusions in lung cancer

23 Sept 2015

Abstract excerpt

Molecular profiling of non-small cell lung cancers (NSCLC) has a strong impact on clinical decision making and current oncological therapies. Besides detection of activating mutations in EGFR, analysis of ALK and ROS1 gene rearrangements has come into focus for targeted therapies. Targeted massive parallel sequencing (MPS) has been established for routine diagnostic profiling of the most prevalent oncogenic...

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PMID: 26394895
DOI: 10.1002/gcc.22297

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