Article
How Rab proteins determine Golgi structure.
International review of cell and molecular biology - 1 Jan 2015
Liu Shijie, Storrie Brian
Abstract excerpt
Rab proteins, small GTPases, are key regulators of mammalian Golgi apparatus organization. Based on the effect of Rab activation state, Rab proteins fall into two functional classes. In Class1, inactivation induces Golgi ribbon fragmentation and/or redistribution of Golgi enzymes to the Endoplasmic Reticulum, while overexpression of wild type or activation has little, if any, effect on Golgi ribbon organization....
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