Article
Rapid degradation of GRASP55 and GRASP65 reveals their immediate impact on the Golgi structure
2020-07-07
Abstract excerpt
GRASP65 and GRASP55 have been implicated in stacking of Golgi cisternae and lateral linking of stacks within the Golgi ribbon. However, loss of gene function approaches by RNAi or gene knockout to dissect their respective roles often resulted in conflicting conclusions. Here, we gene-edited GRASP55 and/or GRASP65 with a degron tag in human fibroblasts, allowing for the induced rapid degradation by the proteasome....
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Identifiers and source
- Literature Corpus work
- be5392da-039b-53b1-a80c-67901f0781ea
- DOI
- 10.1101/2020.07.07.192609