Article
Heritability estimates on Hodgkin's lymphoma: a genomic- versus population-based approach.
European journal of human genetics : EJHG - 1 Jun 2015
Thomsen Hauke, da Silva Filho Miguel Inacio, Försti Asta, Fuchs Michael, Ponader Sabine, von Strandmann Elke Pogge, Eisele Lewin, Herms Stefan, Hofmann Per, Sundquist Jan, Engert Andreas, Hemminki Kari
Abstract excerpt
Genome-wide association studies (GWASs) have identified several single-nucleotide polymorphisms (SNPs) influencing the risk of Hodgkin's lymphoma (HL) and demonstrated the association of common genetic variation for this type of cancer. Such evidence for inherited genetic risk is also provided by the family history and the very high concordance between monozygotic twins. However, little is known about the genetic...
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