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Article

Common alleles contribute to schizophrenia in CNV carriers.

Molecular psychiatry - 1 Aug 2016

Tansey K E, Rees E, Linden D E, Ripke S, Chambert K D, Moran J L, McCarroll S A, Holmans P, Kirov G, Walters J, Owen M J, O'Donovan M C

Abstract excerpt

The genetic architecture of schizophrenia is complex, involving risk alleles ranging from common alleles of weak effect to rare alleles of large effect, the best exemplar of the latter being large copy number variants (CNVs). It is currently unknown whether pathophysiology in those with defined rare mutations overlaps with that in other individuals with the disorder who do not share the same rare mutation. Under...

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Identifiers

PMID: 26390827
DOI: 10.1038/mp.2015.143
PMCID: PMC4960448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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