Article
Gene mutations in malignant lymphoma.
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2016
Chiba Shigeru
Abstract excerpt
Information on the cancer genome has accumulated rapidly, since approximately 2009, with the use of second-generation sequencing technology. Malignant lymphoma is no exception. In mature B-cell lymphomas, which constitute the vast majority of non-Hodgkin lymphomas, frequent mutations are identified in genes involved in signaling pathways, histone-modifying molecules, the DNA damage-response pathway, etc. The...
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