Article
Germline mutations predisposing to diffuse large B-cell lymphoma.
Blood cancer journal - 17 Feb 2017
Leeksma O C, de Miranda N F, Veelken H
Abstract excerpt
Genetic studies of diffuse large B-cell lymphomas (DLBCLs) in humans have revealed numerous targets of somatic mutations and an increasing number of potentially relevant germline alterations. The latter often affect genes involved in DNA repair and/or immune function. In general, defects in these genes also predispose to other conditions. Knowledge of these mutations can lead to disease-preventing measures in the...
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