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New Data on Vaccine Antigen Deficient Bordetella pertussis Isolates

14 Sept 2015

Abstract excerpt

Evolution of Bordetella pertussis is driven by natural and vaccine pressures. Isolates circulating in regions with high vaccination coverage present multiple allelic and antigenic variations as compared to isolates collected before introduction of vaccination. Furthermore, during the last epidemics reported in regions using pertussis acellular vaccines, isolates deficient for vaccine antigens, such as pertactin...

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PMID: 26389958
DOI: 10.3390/vaccines3030751

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