Article
Differences in the genomic content of Bordetella pertussis isolates before and after introduction of pertussis vaccines in four European countries.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2011
Kallonen Teemu, Gröndahl-Yli-Hannuksela Kirsi, Elomaa Annika, Lutyńska Anna, Fry Norman K, Mertsola Jussi, He Qiushui
Abstract excerpt
Resurgence of pertussis has been observed in many countries with high vaccination coverage and clonal expansion of certain Bordetella pertussis strains has been associated with recent epidemics in Europe. It is known that vaccinations have selected strains which are different from those used for vaccine production. However, little is known about the differences in genomic content of strains circulating before the...
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