Article
Analysis of Bordetella pertussis clinical isolates circulating in European countries during the period 1998-2012.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Apr 2015
van Gent M, Heuvelman C J, van der Heide H G, Hallander H O, Advani A, Guiso N, Wirsing von Kőnig C H, Vestrheim D F, Dalby T, Fry N K, Pierard D, Detemmerman L, Zavadilova J, Fabianova K, Logan C, Habington A, Byrne M, Lutyńska A, Mosiej E, Pelaz C, Gröndahl-Yli-Hannuksela K, Barkoff A M, Mertsola J, Economopoulou A, He Q, Mooi F R
Abstract excerpt
Despite more than 50 years of vaccination, pertussis is still an endemic disease, with regular epidemic outbreaks. With the exception of Poland, European countries have replaced whole-cell vaccines (WCVs) by acellular vaccines (ACVs) in the 1990s. Worldwide, antigenic divergence in vaccine antigens has been found between vaccine strains and circulating strains. In this work, 466 Bordetella pertussis isolates...
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