Are there any ethnic differences in molecular predictors of erlotinib efficacy in advanced non-small cell lung cancer?

doi:10.1158/1078-0432.CCR-07-4608

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Are there any ethnic differences in molecular predictors of erlotinib efficacy in advanced non-small cell lung cancer?

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jun 2008

Ahn Myung-Ju, Park Byeong-Bae, Ahn Jin Seok, Kim Sang We, Kim Heung-Tae, Lee Jong Seog, Kang Jin Hyung, Cho Jae Yong, Song Hong Suk, Park Se Hoon, Sohn Chang Hak, Shin Sang Won, Choi Jin Hyuck, Ki Chang-Seok, Park Chan Keum, Holmes Alison J, Jänne Pasi A, Park Keunchil

Abstract excerpt

PURPOSE: This study investigated possible molecular predictors of outcome in Korean patients with advanced non-small cell lung cancer treated with erlotinib. EXPERIMENTAL DESIGN: One hundred and twenty patients received erlotinib and were followed prospectively. Ninety-two tissue samples were analyzed for epidermal growth factor receptor (EGFR) gene mutations (exons 18, 19, and 21), 88 for EGFR gene amplification...

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PMID: 18559606
DOI: 10.1158/1078-0432.CCR-07-4608

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EGFR

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