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Article

Deficiency of P-selectin glycoprotein ligand-1 is protective against the prothrombotic effects of interleukin-1β.

Journal of thrombosis and haemostasis : JTH - 1 Dec 2015

Wang H, Kleiman K, Wang J, Luo W, Guo C, Eitzman D T

Abstract excerpt

BACKGROUND: Proinflammatory cytokines are associated with cardiovascular diseases, including acute and recurrent myocardial infarction. However, the causal role of cytokines in thrombotic complications of atherosclerosis remains unclear. Interleukin-1β (IL-1β) is currently being targeted in a human clinical trial for the prevention of ischemic events. OBJECTIVES: The purpose of the present study was to test the...

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Source

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Identifiers

PMID: 26386314
DOI: 10.1111/jth.13146
PMCID: PMC4715499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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