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Non-p.V600E BRAF Mutations Are Common Using a More Sensitive and Broad Detection Tool

18 Sept 2015

Abstract excerpt

OBJECTIVES: To assess the performance of a next-generation sequencing (NGS) platform for the clinical detection of BRAF mutations. METHODS: In this retrospective quality assessment of an NGS assay, we analyzed BRAF mutations within parts of exons 11 and 15 in 835 neoplastic tissues submitted to our molecular diagnostics laboratory. RESULTS: The NGS assays detected a BRAF mutation in 5.9% of lung adenocarcinomas,...

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PMID: 26386083
DOI: 10.1309/ajcp85atmjozoudj

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